Tibesaikosaponin V

Modify Date: 2024-04-06 09:14:11

Tibesaikosaponin V Structure
Tibesaikosaponin V structure
Common Name Tibesaikosaponin V
CAS Number 2319668-87-4 Molecular Weight 812.98
Density 1.40±0.1 g/cm3(Predicted) Boiling Point 950.9±65.0 °C(Predicted)
Molecular Formula C42H68O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tibesaikosaponin V


Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders[1].

 Names

Name Tibesaikosaponin V
Synonym More Synonyms

 Tibesaikosaponin V Biological Activity

Description Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders[1].
Related Catalog
Target

PPARγ

References

[1]. Feng Y, et al. A new triterpene diglycoside from the roots of Bupleurum chinense DC. and its inhibitory effect on adipogensis in 3T3-L1 cells[J]. Medicinal Chemistry Research, 2019, 28: 239-245.

 Chemical & Physical Properties

Density 1.40±0.1 g/cm3(Predicted)
Boiling Point 950.9±65.0 °C(Predicted)
Molecular Formula C42H68O15
Molecular Weight 812.98

 Synonyms

Olean-12-en-16-one, 3-[(6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranosyl)oxy]-11,15,23,28-tetrahydroxy-, (3β,4α,15α)-
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