8-Br-GTP
Modify Date: 2024-01-02 16:26:18
8-Br-GTP structure
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Common Name | 8-Br-GTP | ||
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| CAS Number | 23197-98-0 | Molecular Weight | 602.07600 | |
| Density | 2.89g/cm3 | Boiling Point | 1354.2ºC at 760 mmHg | |
| Molecular Formula | C10H15BrN5O14P3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 772.8ºC | |
Use of 8-Br-GTP8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification[1]. |
| Name | [[(2R,3S,4R,5R)-5-(2-amino-1-bromo-6-oxopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
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| Synonym | More Synonyms |
| Description | 8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification[1]. |
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| Related Catalog | |
| In Vitro | 8-Br-GTP inhibits FtsZ polymerization but does not affect tubulin polymerization.8-Br-GTP has two stable orientations of the base toward the sugar: anti and syn. 8-Br-GTP shows preference for the syn conformation (population ~90%)[1][2]. |
| References |
| Density | 2.89g/cm3 |
|---|---|
| Boiling Point | 1354.2ºC at 760 mmHg |
| Molecular Formula | C10H15BrN5O14P3 |
| Molecular Weight | 602.07600 |
| Flash Point | 772.8ºC |
| Exact Mass | 600.90100 |
| PSA | 328.53000 |
| Vapour Pressure | 0mmHg at 25°C |
|
~68%
8-Br-GTP CAS#:23197-98-0 |
| Literature: Gordeeva, L. S.; Kaminskii, Yu. L.; Rumyantseva, L. N.; Patokina, N. A.; Korsakova, N. A.; et al. Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 729 - 733 Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 771 - 776 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 8-Bromo-GTP |
| 8-bromoguanosine triphosphate |
| 8-bromoguanosine 5'-triphosphate |