BI-3663
Modify Date: 2024-01-20 11:46:50
BI-3663 structure
|
Common Name | BI-3663 | ||
|---|---|---|---|---|
| CAS Number | 2341740-84-7 | Molecular Weight | 917.839 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C44H42F3N7O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI-3663BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-446 |
| Name | BI-3663 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C44H42F3N7O12 |
| Molecular Weight | 917.839 |
| Exact Mass | 917.284363 |
| LogP | 2.31 |
| Index of Refraction | 1.627 |
| 5,8,11-Trioxa-2-azatetradecan-14-amide, 1-[4-[[4-[(2,3-dihydro-3-oxo-1H-inden-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-3-methoxyphenyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-oxo- |
| N-[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-1-[3-methoxy-4-({4-[(3-oxo-2,3-dihydro-1H-inden-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl}amino)phenyl]-1-oxo-5,8,11-trioxa-2-azatetradecan-14-amide |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: BI-3663
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
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