CRBN-6-5-5-VHL

Modify Date: 2024-01-09 12:10:55

CRBN-6-5-5-VHL Structure
CRBN-6-5-5-VHL structure
 Common Name CRBN-6-5-5-VHL
CAS Number 2362575-45-7 Molecular Weight 972.20
Density N/A Boiling Point N/A
Molecular Formula C51H69N7O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CRBN-6-5-5-VHL


CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].

 Names

Name CRBN-6-5-5-VHL

 CRBN-6-5-5-VHL Biological Activity

Description CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].
Related Catalog
Target

Cereblon:1.5 nM (DC50)

References

[1]. Christian Steinebach, et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824.

 Chemical & Physical Properties

Molecular Formula C51H69N7O10S
Molecular Weight 972.20

 Safety Information

Hazard Codes Xi
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Chemsrc provides CRBN-6-5-5-VHL(CAS#:2362575-45-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CRBN-6-5-5-VHL are included as well.>> amp version: CRBN-6-5-5-VHL

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