Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CRBN-6-5-5-VHL
Price:
Purity: 96.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: CRBN-6-5-5-VHL
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2362575-45-7

2362575-45-7 structure

2362575-45-7 structure

Name: CRBN-6-5-5-VHL
Chemical Name: CRBN-6-5-5-VHL
CAS Number: 2362575-45-7
Molecular Formula: C₅₁H₆₉N₇O₁₀S
Molecular Weight: 972.20
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2020-10-19 16:09:49
Modify Date: 2024-01-09 12:10:55
CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].

Name	CRBN-6-5-5-VHL

Description	CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC
Target	Cereblon:1.5 nM (DC50)
References	[1]. Christian Steinebach, et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824.

Molecular Formula	C₅₁H₆₉N₇O₁₀S
Molecular Weight	972.20

Hazard Codes	Xi