ZN-c3
Modify Date: 2024-01-06 11:24:51
ZN-c3 structure
|
Common Name | ZN-c3 | ||
|---|---|---|---|---|
| CAS Number | 2376146-48-2 | Molecular Weight | 526.63 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H34N8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZN-c3ZN-c3 is an orally active, highly potent and selective Wee1 inhibitor (IC50=3.9 nM). ZN-c3 can be used for the research of cancer[1]. |
| Name | ZN-c3 |
|---|
| Description | ZN-c3 is an orally active, highly potent and selective Wee1 inhibitor (IC50=3.9 nM). ZN-c3 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 3.9 nM (Wee1)[1] |
| In Vitro | ZN-c3 IC50 is 103 nM in H23c cells[1]. |
| In Vivo | ZN-c3 (80 mg/kg; p.o.; 28 days) can effectively shrank tumors at 80 mg/kg as a single agent[1]. ZN-c3 shows excellent exposures and bioavailability in the dog PK study[1]. |
| References |
| Molecular Formula | C29H34N8O2 |
|---|---|
| Molecular Weight | 526.63 |
| Storage condition | -20°C |