PI3KC2α-IN-2

Modify Date: 2024-01-28 19:50:08

PI3KC2α-IN-2 Structure
PI3KC2α-IN-2 structure
Common Name PI3KC2α-IN-2
CAS Number 2397679-77-3 Molecular Weight 516.59
Density N/A Boiling Point N/A
Molecular Formula C25H20N6O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3KC2α-IN-2


PI3KC2α-IN-2 is a potent and selective PI3KC2α inhibitor (IC50: 121 nM). PI3KC2α-IN-2 interacts with the ATP-binding site of PI3KC2α.. PI3KC2α-IN-2 can be used in the research of thrombosis, diabetes and cancers[1].

 Names

Name PI3KC2α-IN-2

 PI3KC2α-IN-2 Biological Activity

Description PI3KC2α-IN-2 is a potent and selective PI3KC2α inhibitor (IC50: 121 nM). PI3KC2α-IN-2 interacts with the ATP-binding site of PI3KC2α.. PI3KC2α-IN-2 can be used in the research of thrombosis, diabetes and cancers[1].
Related Catalog
Target

PI3KC2α:121 nM (IC50)

PI3KC2β:1399 nM (IC50)

PI3KC2γ:>10 μM (IC50)

In Vitro PI3KC2α-IN-2 (PITCOIN2) is selective against PI3KC2γ but showed micromolar activity on PI3KC2β[1].

 Chemical & Physical Properties

Molecular Formula C25H20N6O3S2
Molecular Weight 516.59