OM-1700

Modify Date: 2024-01-10 06:47:12

OM-1700 structure	Common Name	OM-1700
	CAS Number	2406276-78-4	Molecular Weight	458.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₃FN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of OM-1700

OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1].

Name	OM-1700

Description	OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	TNKS1:127 nM (IC50) TNKS2:14 nM (IC50)
In Vitro	OM-153 shows inhibition (IC50=19 nM) in a cellular (HEK293) WNT/β-catenin signaling reporter assay[1].
References	[1]. Leenders RGG, et al. Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II. J Med Chem. 2021;64(24):17936-17949.

Molecular Formula	C₂₅H₂₃FN₆O₂
Molecular Weight	458.49

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: OM-1700
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: OM-1700
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Chemical & Physical Properties