Anti-inflammatory agent 21

Modify Date: 2024-01-09 15:18:48

Anti-inflammatory agent 21 Structure
Anti-inflammatory agent 21 structure
Common Name Anti-inflammatory agent 21
CAS Number 2408836-40-6 Molecular Weight 424.42
Density N/A Boiling Point N/A
Molecular Formula C24H21FO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-inflammatory agent 21


Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1].

 Names

Name Anti-inflammatory agent 21

 Anti-inflammatory agent 21 Biological Activity

Description Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1].
Related Catalog
Target

IC50: 0.76 μM (NO)[1]

References

[1]. Chen LZ, Wu J, Li K, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020;206:112722.

 Chemical & Physical Properties

Molecular Formula C24H21FO6
Molecular Weight 424.42