Imlunestrant

Modify Date: 2024-01-02 22:45:42

Imlunestrant structure	Common Name	Imlunestrant
	CAS Number	2408840-26-4	Molecular Weight	524.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₄F₄N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Imlunestrant

Imlunestrant (LY3484356) is an orally active selective estrogen receptor (ER) degrader (SERD). Imlunestrant (LY3484356) could be used in the study for ER+, HER2-advanced breast cancer[1].

Name	Imlunestrant

Description	Imlunestrant (LY3484356) is an orally active selective estrogen receptor (ER) degrader (SERD). Imlunestrant (LY3484356) could be used in the study for ER+, HER2-advanced breast cancer[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Cancer
In Vitro	Imlunestrant (LY3484356) shows favorable efficacy and pharmacokinetic (PK) properties, including antitumor activity in ESR1 mutants[1]. Imlunestrant (LY3484356) is a potent degrader and selective pure antagonist of wild type and mutant ERα[2].
References	[1]. Komal L. Jhaveri, et al. A first-in-human phase 1a/b trial of LY3484356, an oral selective estrogen receptor (ER) degrader (SERD) in ER+ advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC): Results from the EMBER study. 2021 ASCO Annual Meeting I. [2]. Cristina Hernando, et al. Oral Selective Estrogen Receptor Degraders (SERDs) as a Novel Breast Cancer Therapy: Present and Future from a Clinical Perspective. Int. J. Mol. Sci. 2021, 22(15), 7812.

Molecular Formula	C₂₉H₂₄F₄N₂O₃
Molecular Weight	524.51

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Imlunestrant
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Imlunestrant
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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