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2408840-26-4 2408840-41-3
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2408840-26-4

2408840-26-4 structure
2408840-26-4 structure
  • Name: Imlunestrant
  • Chemical Name: Imlunestrant
  • CAS Number: 2408840-26-4
  • Molecular Formula: C29H24F4N2O3
  • Molecular Weight: 524.51
  • Catalog: Research Areas Cancer
  • Create Date: 2022-03-28 18:14:55
  • Modify Date: 2024-01-02 22:45:42
  • Imlunestrant (LY3484356) is an orally active selective estrogen receptor (ER) degrader (SERD). Imlunestrant (LY3484356) could be used in the study for ER+, HER2-advanced breast cancer[1].
Name Imlunestrant
Description Imlunestrant (LY3484356) is an orally active selective estrogen receptor (ER) degrader (SERD). Imlunestrant (LY3484356) could be used in the study for ER+, HER2-advanced breast cancer[1].
Related Catalog
In Vitro Imlunestrant (LY3484356) shows favorable efficacy and pharmacokinetic (PK) properties, including antitumor activity in ESR1 mutants[1]. Imlunestrant (LY3484356) is a potent degrader and selective pure antagonist of wild type and mutant ERα[2].
References

[1]. Komal L. Jhaveri, et al. A first-in-human phase 1a/b trial of LY3484356, an oral selective estrogen receptor (ER) degrader (SERD) in ER+ advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC): Results from the EMBER study. 2021 ASCO Annual Meeting I.

[2]. Cristina Hernando, et al. Oral Selective Estrogen Receptor Degraders (SERDs) as a Novel Breast Cancer Therapy: Present and Future from a Clinical Perspective. Int. J. Mol. Sci. 2021, 22(15), 7812.
Molecular Formula C29H24F4N2O3
Molecular Weight 524.51

Chemsrc provides CAS#:2408840-26-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2408840-26-4 | Chemsrc address: https://www.chemsrc.com/en/baike/1704076.html

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