Thalidomide-O-PEG4-Boc

Modify Date: 2024-01-10 07:48:47

Thalidomide-O-PEG4-Boc Structure
Thalidomide-O-PEG4-Boc structure
Common Name Thalidomide-O-PEG4-Boc
CAS Number 2411681-87-1 Molecular Weight 578.61
Density N/A Boiling Point N/A
Molecular Formula C28H38N2O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-PEG4-Boc


Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thalidomide-O-PEG4-Boc

 Thalidomide-O-PEG4-Boc Biological Activity

Description Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H38N2O11
Molecular Weight 578.61

 Safety Information

Hazard Codes Xi