2380318-57-8

2380318-57-8 structure
2380318-57-8 structure
  • Name: Thalidomide-O-PEG4-azide
  • Chemical Name: Thalidomide-O-PEG4-azide
  • CAS Number: 2380318-57-8
  • Molecular Formula: C23H29N5O9
  • Molecular Weight: 519.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:14:14
  • Modify Date: 2024-01-05 11:34:31
  • Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Thalidomide-O-PEG4-azide
Description Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H29N5O9
Molecular Weight 519.50
Hazard Codes Xi