Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Thalidomide-O-PEG4-azide
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2380318-57-8

2380318-57-8 structure

2380318-57-8 structure

Name: Thalidomide-O-PEG4-azide
Chemical Name: Thalidomide-O-PEG4-azide
CAS Number: 2380318-57-8
Molecular Formula: C₂₃H₂₉N₅O₉
Molecular Weight: 519.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 07:14:14
Modify Date: 2024-01-05 11:34:31
Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Thalidomide-O-PEG4-azide

Description	Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₂₉N₅O₉
Molecular Weight	519.50

Hazard Codes	Xi