USP7-IN-7
Modify Date: 2024-04-05 18:52:37
USP7-IN-7 structure
|
Common Name | USP7-IN-7 | ||
|---|---|---|---|---|
| CAS Number | 2413944-70-2 | Molecular Weight | 510.05 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28ClN3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of USP7-IN-7USP7-IN-7 (compound 124) is a USP7 inhibitor with an IC50 value ＜10 nM. USP7-IN-7 shows cytotoxicity against p53-mutant cancer cell lines, p53 wild-type blood cancer and neuroblastoma cell lines with low nanomolar values. USP7-IN-7 can be used for cancer research[1]. |
| Name | USP7-IN-7 |
|---|
| Description | USP7-IN-7 (compound 124) is a USP7 inhibitor with an IC50 value ＜10 nM. USP7-IN-7 shows cytotoxicity against p53-mutant cancer cell lines, p53 wild-type blood cancer and neuroblastoma cell lines with low nanomolar values. USP7-IN-7 can be used for cancer research[1]. |
|---|---|
| Related Catalog | |
| In Vitro | USP7-IN-7 (0-1 μM) 对 p53 野生型血液癌细胞系具有细胞毒性，对 M07e，OCI-AML5，MOLM13 和 MM.IS 的 CC50 值分别为 0.2，0.2，0.4 和 0.1 μM[1]。 USP7-IN-7 (0-2 μM) 对 p53 野生型神经母细胞瘤细胞株具有细胞毒性，对 SH-SY5Y，CHP-134 和 NB-1 的 CC50 值分别为 1.9，0.6 和 0.5 μM[1]。 USP7-IN-7 (0-25 μM) 对 p53 突变癌细胞系具有细胞毒性，对 H526，LA-N-2 和 SK-N-DZ 的 CC50 值分别为 0.5，0.2 和 0.2 μM[1]。 |
| References |
| Molecular Formula | C27H28ClN3O3S |
|---|---|
| Molecular Weight | 510.05 |