PDE4-IN-8
Modify Date: 2024-01-09 19:22:02
PDE4-IN-8 structure
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Common Name | PDE4-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2415085-45-7 | Molecular Weight | 327.18 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H22BNO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PDE4-IN-8PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1]. |
| Name | PDE4-IN-8 |
|---|
| Description | PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1]. |
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| Related Catalog | |
| Target |
PDE4B2:0.93 nM (IC50) IL4:36.33 nM (IC50) IL-13:4.04 nM (IC50) |
| References |
[1]. Joseph Walter Strohbach, et al. Inhibiteurs de pde4 contenant du bore. WO2020070651A1. |
| Molecular Formula | C18H22BNO4 |
|---|---|
| Molecular Weight | 327.18 |