Anti-MRSA agent 3

Modify Date: 2024-01-15 19:07:32

Anti-MRSA agent 3 structure	Common Name	Anti-MRSA agent 3
	CAS Number	2416909-42-5	Molecular Weight	520.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₁₈BrN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anti-MRSA agent 3

Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].

Name	Anti-MRSA agent 3

Description	Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	MIC: 0.098 μg/ml (MRSA)[1]
In Vivo	Anti-MRSA agent 3 has potent efficacy at a dose of 10 mg/kg (20% survival) in a mouse peritonitis model[1].
References	[1]. Wang X, et al. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo. Eur J Med Chem. 2022;230:114099.

Molecular Formula	C₂₉H₁₈BrN₃O₂
Molecular Weight	520.38

Anti-MRSA agent 3

Use of Anti-MRSA agent 3

Names

Anti-MRSA agent 3 Biological Activity

Chemical & Physical Properties