FGFR4-IN-12

Modify Date: 2024-01-10 10:35:56

FGFR4-IN-12 Structure
FGFR4-IN-12 structure
Common Name FGFR4-IN-12
CAS Number 2423992-63-4 Molecular Weight 663.55
Density N/A Boiling Point N/A
Molecular Formula C34H32Cl2N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR4-IN-12


FGFR4-IN-12 (Compound A34) is a potent inhibitor of FGFR4. FGFR4-IN-12 exhibits improved FGFR4 inhibitory capability and selectivity and excellent anti-proliferative activities against FGFR4-dependent HCC cell lines. FGFR4-IN-12 has the potential for the research of cancer diseases[1].

 Names

Name FGFR4-IN-12

 FGFR4-IN-12 Biological Activity

Description FGFR4-IN-12 (Compound A34) is a potent inhibitor of FGFR4. FGFR4-IN-12 exhibits improved FGFR4 inhibitory capability and selectivity and excellent anti-proliferative activities against FGFR4-dependent HCC cell lines. FGFR4-IN-12 has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. Zhang X, et al. Discovery of 1,6-Naphthyridin-2(1H)-one Derivatives as Novel, Potent, and Selective FGFR4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022;65(11):7595-7618.

 Chemical & Physical Properties

Molecular Formula C34H32Cl2N4O6
Molecular Weight 663.55