hCAI/II-IN-5
Modify Date: 2024-01-09 14:31:58
hCAI/II-IN-5 structure
|
Common Name | hCAI/II-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 2428389-67-5 | Molecular Weight | 581.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H18Cl2N8O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of hCAI/II-IN-5hCAI/II-IN-5 (compound MZ8) is a potent hCA I and hCA II (human carbonic anhydrase isoenzymes I and II) inhibitor, with IC50 values of 37.88 and 45.23 nM, respectively. hCAI/II-IN-5 also shows inhibition profile against α-Glycosidase and AChE, with IC50 values of 48.98 and 420.14 nM, respectively. hCAI/II-IN-5 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy[1]. |
| Name | hCAI/II-IN-5 |
|---|
| Description | hCAI/II-IN-5 (compound MZ8) is a potent hCA I and hCA II (human carbonic anhydrase isoenzymes I and II) inhibitor, with IC50 values of 37.88 and 45.23 nM, respectively. hCAI/II-IN-5 also shows inhibition profile against α-Glycosidase and AChE, with IC50 values of 48.98 and 420.14 nM, respectively. hCAI/II-IN-5 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 37.88 ± 0.9956 nM (hCA II), 45.23 ± 0.9684 nM (hCA I), 48.98 ± 0.9407 nM (α-GLY), 420.14 ± 0.9759 nM (AChE); KI: 40.35 ± 5.74 nM (hCA II), 50.04 ± 5.76 nM (α-GLY), 51.67 ± 4.76 nM (hCA I), 363.96 ± 32.87 nM (AChE)[1] |
| References |
| Molecular Formula | C21H18Cl2N8O4S2 |
|---|---|
| Molecular Weight | 581.45 |