VIM-2-IN-1

Modify Date: 2024-01-06 04:36:42

VIM-2-IN-1 Structure
VIM-2-IN-1 structure
Common Name VIM-2-IN-1
CAS Number 2452118-54-4 Molecular Weight 436.23
Density N/A Boiling Point N/A
Molecular Formula C12H13IN4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VIM-2-IN-1


VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].

 Names

Name VIM-2-IN-1

 VIM-2-IN-1 Biological Activity

Description VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].
Related Catalog
Target

IC50: 23 µM (VIM-2), 48 µM (GIM-1) and 231 µM (NDM-1)[1].

References

[1]. Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28(15):115598.

 Chemical & Physical Properties

Molecular Formula C12H13IN4O4S
Molecular Weight 436.23