PI3K/Akt/mTOR-IN-3

Modify Date: 2024-01-09 16:30:48

PI3K/Akt/mTOR-IN-3 structure	Common Name	PI3K/Akt/mTOR-IN-3
	CAS Number	2457245-94-0	Molecular Weight	505.77
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₅₁NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PI3K/Akt/mTOR-IN-3

PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].

Name	PI3K/Akt/mTOR-IN-3

Description	PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Wang SS, et al. Synthesis and antitumor activity of α,β-unsaturated carbonyl moiety- containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway. Bioorg Chem. 2020 Aug;101:104036.

Molecular Formula	C₃₄H₅₁NO₂
Molecular Weight	505.77

PI3K/Akt/mTOR-IN-3

Use of PI3K/Akt/mTOR-IN-3

Names

PI3K/Akt/mTOR-IN-3 Biological Activity

Chemical & Physical Properties