NS2B/NS3-IN-6

Modify Date: 2024-04-06 23:02:53

NS2B/NS3-IN-6 Structure
NS2B/NS3-IN-6 structure
Common Name NS2B/NS3-IN-6
CAS Number 2459657-57-7 Molecular Weight 433.50
Density N/A Boiling Point N/A
Molecular Formula C19H19N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NS2B/NS3-IN-6


NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].

 Names

Name NS2B/NS3-IN-6

 NS2B/NS3-IN-6 Biological Activity

Description NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].
Related Catalog
Target

IC50: 2.23 µM (ZIKV NS2B/NS3 protease), 25.2 µM (DENV NS2B/NS3 protease)[1]

References

[1]. Maus H, et al. SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases. Bioorg Med Chem. 2021 Oct 1;47:116392.

 Chemical & Physical Properties

Molecular Formula C19H19N3O5S2
Molecular Weight 433.50