2459657-57-7

2459657-57-7 structure

2459657-57-7 structure

Name: NS2B/NS3-IN-6
Chemical Name: NS2B/NS3-IN-6
CAS Number: 2459657-57-7
Molecular Formula: C₁₉H₁₉N₃O₅S₂
Molecular Weight: 433.50
Catalog: Research Areas Infection
Create Date: 2022-08-12 17:10:47
Modify Date: 2024-04-06 23:02:53
NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].

Name	NS2B/NS3-IN-6

Description	NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 2.23 µM (ZIKV NS2B/NS3 protease), 25.2 µM (DENV NS2B/NS3 protease)[1]
References	[1]. Maus H, et al. SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases. Bioorg Med Chem. 2021 Oct 1;47:116392.

Molecular Formula	C₁₉H₁₉N₃O₅S₂
Molecular Weight	433.50