PARP1-IN-11

Modify Date: 2024-04-08 13:51:35

PARP1-IN-11 Structure
PARP1-IN-11 structure
Common Name PARP1-IN-11
CAS Number 2482484-87-5 Molecular Weight 296.28
Density N/A Boiling Point N/A
Molecular Formula C16H12N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PARP1-IN-11


PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].

 Names

Name PARP1-IN-11

 PARP1-IN-11 Biological Activity

Description PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].
Related Catalog
Target

PARP1:0.082 μM (IC50)

PARP2

TNKS1

TNKS2

References

[1]. Shao X, et al. Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors. Bioorg Chem. 2020 Sep;102:104075.

 Chemical & Physical Properties

Molecular Formula C16H12N2O4
Molecular Weight 296.28