EZH2-IN-17

Modify Date: 2024-01-20 19:30:38

EZH2-IN-17 structure	Common Name	EZH2-IN-17
	CAS Number	2489672-09-3	Molecular Weight	598.77
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₄₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EZH2-IN-17

EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1].

Name	EZH2-IN-17

Description	EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
References	[1]. Xin Xu, et al. Conformationally constrained potent inhibitors for enhancer of zeste homolog 2 (EZH2). Bioorg Med Chem Lett. 2023 Nov 11:129558.

Molecular Formula	C₃₆H₄₆N₄O₄
Molecular Weight	598.77

EZH2-IN-17

Use of EZH2-IN-17

Names

EZH2-IN-17 Biological Activity

Chemical & Physical Properties