Enniatin A

Modify Date: 2024-01-11 17:13:20

Enniatin A Structure
Enniatin A structure
Common Name Enniatin A
CAS Number 2503-13-1 Molecular Weight 681.90000
Density 1.022±0.06 g/cm3 Boiling Point 847.4±65.0 °C
Molecular Formula C36H63N3O9 Melting Point 122-124 °C
MSDS USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of Enniatin A


Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1].

 Names

Name enniatin A
Synonym More Synonyms

 Enniatin A Biological Activity

Description Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1].
Related Catalog
Target

ACAT

In Vitro Enniatin A exhibits cytotoxic effects in HeLa cell lines with IC50s of 1.15 μM concentration for 24 h and 0.57 μM concentration for 48 h[2].
References

[1]. Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32.

[2]. Mamur S, et al. Assessment of cytotoxic and genotoxic effects of enniatin-A in vitro. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Aug;35(8):1633-1644.

 Chemical & Physical Properties

Density 1.022±0.06 g/cm3
Boiling Point 847.4±65.0 °C
Melting Point 122-124 °C
Molecular Formula C36H63N3O9
Molecular Weight 681.90000
Exact Mass 681.45600
PSA 139.83000
LogP 4.13640
Vapour Pressure 5.53E-29mmHg at 25°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H311-H331
Precautionary Statements P261-P280-P301 + P310-P311
Hazard Codes T
Risk Phrases 23/24/25
RIDADR UN 2811

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

ENNIATIN A (LATERITIN I)
ENNIATIN A
Enniatin-A