Enniatin A1

Modify Date: 2024-01-03 04:11:51

Enniatin A1 Structure
Enniatin A1 structure
Common Name Enniatin A1
CAS Number 4530-21-6 Molecular Weight 667.87400
Density N/A Boiling Point N/A
Molecular Formula C35H61N3O9 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of Enniatin A1


Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids. Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes[1].

 Names

Name enniatin A1

 Enniatin A1 Biological Activity

Description Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids. Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes[1].
Related Catalog
Target

ERK

References

[1]. Wätjen W, et al. Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Mol Nutr Food Res. 2009 Apr;53(4):431-40.

 Chemical & Physical Properties

Molecular Formula C35H61N3O9
Molecular Weight 667.87400
Exact Mass 667.44100
PSA 139.83000
LogP 3.74630
Storage condition -20°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H311-H331
Precautionary Statements P261-P280-P301 + P310-P311
RIDADR UN 3462 6.1 / PGIII