NNC 63-0532

Modify Date: 2024-01-12 11:11:34

NNC 63-0532 Structure
NNC 63-0532 structure
Common Name NNC 63-0532
CAS Number 250685-44-0 Molecular Weight 443.53700
Density 1.28g/cm3 Boiling Point 645.8ºC at 760mmHg
Molecular Formula C27H29N3O3 Melting Point N/A
MSDS Chinese Flash Point 344.4ºC

 Use of NNC 63-0532


NNC63-0532 is a novel non-peptide nociceptin receptor (ORL1) agonist, with EC50s of 305?nM. NNC63-0532 plays important roles in many disorders such as pain, drug addiction[1].

 Names

Name methyl 2-[8-(naphthalen-2-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate
Synonym More Synonyms

 NNC 63-0532 Biological Activity

Description NNC63-0532 is a novel non-peptide nociceptin receptor (ORL1) agonist, with EC50s of 305?nM. NNC63-0532 plays important roles in many disorders such as pain, drug addiction[1].
Related Catalog
References

[1]. C Thomsen, et al. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8.  

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 645.8ºC at 760mmHg
Molecular Formula C27H29N3O3
Molecular Weight 443.53700
Flash Point 344.4ºC
Exact Mass 443.22100
PSA 53.09000
LogP 3.59450
Vapour Pressure 1.44E-16mmHg at 25°C
Index of Refraction 1.675
Storage condition -20°C

 Synonyms

Tocris-1780
HMS3268G04
Salvinorin A
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