TGFβRI-IN-5

Modify Date: 2024-04-27 11:17:39

TGFβRI-IN-5 structure	Common Name	TGFβRI-IN-5
	CAS Number	2541690-15-5	Molecular Weight	328.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₂N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TGFβRI-IN-5

TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].

Name	TGFβRI-IN-5

Description	TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Ismail MMF, et al. Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors. Bioorg Chem. 2020;105:104368.

Molecular Formula	C₁₆H₁₂N₂O₆
Molecular Weight	328.28

TGFβRI-IN-5

Use of TGFβRI-IN-5

Names

TGFβRI-IN-5 Biological Activity

Chemical & Physical Properties