SIRT6-IN-5
Modify Date: 2024-02-04 08:55:55
SIRT6-IN-5 structure
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Common Name | SIRT6-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 891002-11-2 | Molecular Weight | 366.32 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 461.6±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H14N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 233.0±28.7 °C | |
Use of SIRT6-IN-5SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1]. |
| Name | 5-{[4-(2-Furoylamino)benzoyl]amino}-2-hydroxybenzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1]. |
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| Related Catalog | |
| Target |
SIRT6[1] |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 461.6±45.0 °C at 760 mmHg |
| Molecular Formula | C19H14N2O6 |
| Molecular Weight | 366.32 |
| Flash Point | 233.0±28.7 °C |
| Exact Mass | 366.085175 |
| LogP | 3.39 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.733 |
| 5-{[4-(2-Furoylamino)benzoyl]amino}-2-hydroxybenzoic acid |
| MFCD07114223 |
| Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- |