Sulfo DBCO-PEG3-acid

Modify Date: 2024-04-03 18:47:27

Sulfo DBCO-PEG3-acid Structure
Sulfo DBCO-PEG3-acid structure
Common Name Sulfo DBCO-PEG3-acid
CAS Number 2566404-75-7 Molecular Weight 659.70
Density N/A Boiling Point N/A
Molecular Formula C31H37N3O11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sulfo DBCO-PEG3-acid


Sulfo DBCO-PEG3-acid is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].

 Names

Name Sulfo DBCO-PEG3-acid

 Sulfo DBCO-PEG3-acid Biological Activity

Description Sulfo DBCO-PEG3-acid is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C31H37N3O11S
Molecular Weight 659.70