2055198-07-5

2055198-07-5 structure
2055198-07-5 structure
  • Name: Sulfo DBCO-PEG4-Maleimide
  • Chemical Name: Sulfo DBCO-PEG4-Maleimide
  • CAS Number: 2055198-07-5
  • Molecular Formula: C39H47N5O13S
  • Molecular Weight: 825.88
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:26:47
  • Modify Date: 2024-01-11 07:21:27
  • Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Sulfo DBCO-PEG4-Maleimide
Synonyms MFCD30458040
Description Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C39H47N5O13S
Molecular Weight 825.88