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1480516-75-3

1480516-75-3 structure
1480516-75-3 structure
  • Name: DBCO-PEG4-Maleimide
  • Chemical Name: N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-19-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-amide
  • CAS Number: 1480516-75-3
  • Molecular Formula: C36H42N4O9
  • Molecular Weight: 674.740
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-04 04:20:56
  • Modify Date: 2024-04-03 15:37:34
  • DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-19-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-amide
Synonyms 1H-Pyrrole-1-propanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15,19-dioxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]-2,5-dihydro-2,5-dioxo-
N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-19-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-amide
Description DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Xiaotian Zhong, et al. Capped and uncapped antibody cysteines, and their use in antibody-drug conjugation. WO2017025897A2.

Density 1.3±0.1 g/cm3
Boiling Point 965.2±65.0 °C at 760 mmHg
Molecular Formula C36H42N4O9
Molecular Weight 674.740
Flash Point 537.6±34.3 °C
Exact Mass 674.295166
LogP 1.22
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.616
Storage condition -20°C