2110448-99-0

2110448-99-0 structure
2110448-99-0 structure
  • Name: DBCO-PEG4-acid
  • Chemical Name: DBCO-PEG4-acid
  • CAS Number: 2110448-99-0
  • Molecular Formula: C30H36N2O8
  • Molecular Weight: 552.62
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-12-28 10:47:41
  • Modify Date: 2024-01-29 18:18:39
  • DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-PEG4-acid
Description DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C30H36N2O8
Molecular Weight 552.62