2353410-17-8

2353410-17-8 structure
2353410-17-8 structure
  • Name: DBCO-PEG4-NH-Boc
  • Chemical Name: DBCO-PEG4-NH-Boc
  • CAS Number: 2353410-17-8
  • Molecular Formula: C34H45N3O8
  • Molecular Weight: 623.74
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:22:52
  • Modify Date: 2024-01-10 10:56:15
  • DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-PEG4-NH-Boc
Description DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C34H45N3O8
Molecular Weight 623.74