(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol

Modify Date: 2024-01-02 16:45:12

(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol Structure
(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol structure
Common Name (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol
CAS Number 25695-95-8 Molecular Weight 299.492
Density 0.9±0.1 g/cm3 Boiling Point 445.9±45.0 °C at 760 mmHg
Molecular Formula C18H37NO2 Melting Point N/A
MSDS N/A Flash Point 223.5±28.7 °C

 Use of (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol


L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect[1].

 Names

Name (2S,3S,4E)-L-threo sphingosine
Synonym More Synonyms

 (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol Biological Activity

Description L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect[1].
Related Catalog
References

[1]. Sakakura C, et al. Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine. Biochem Biophys Res Commun. 1998 May 29;246(3):827-30.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 445.9±45.0 °C at 760 mmHg
Molecular Formula C18H37NO2
Molecular Weight 299.492
Flash Point 223.5±28.7 °C
Exact Mass 299.282440
PSA 66.48000
LogP 6.40
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.489

 Synonyms

(2S,3S,4E)-2-Amino-octadec-4-ene-1,3-diol
L-(-)-Threosphingenine
(2S,3S,4E)-L-threo-sphingosine
L-threo-sphingosine
4-Octadecene-1,3-diol, 2-amino-, (2S,3S,4E)-
(-)-(E,2S,3S)-2-aminooctadec-4-ene-1,3-diol
(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol
(E)-(2S,3S)-2-Amino-octadec-4-ene-1,3-diol
(2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol
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