Synstab A

Modify Date: 2024-01-16 17:02:19

Synstab A structure	Common Name	Synstab A
	CAS Number	257612-36-5	Molecular Weight	501.61
	Density	1.73g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₃BrCl₃N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Synstab A

Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].

Name	4-bromo-N-[2,2,2-trichloro-1-(4-sulfamoylanilino)ethyl]benzamide

Description	Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	α-Tubulin and β-Tubulin interaction[1]
References	[1]. Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378. [2]. Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.

Density	1.73g/cm3
Molecular Formula	C₁₅H₁₃BrCl₃N₃O₃S
Molecular Weight	501.61
Exact Mass	498.89300
PSA	109.67000
LogP	5.87970
Index of Refraction	1.663