LEP(116-130)(mouse) structure
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Common Name | LEP(116-130)(mouse) | ||
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CAS Number | 258276-95-8 | Molecular Weight | 1560.73000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C64H109N19O24S | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Use of LEP(116-130)(mouse)LEP(116-130)(mouse) is a synthetic leptin peptide fragment. |
Name | Leptin Fragment 116-130 Amide mouse |
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Synonym | More Synonyms |
Description | LEP(116-130)(mouse) is a synthetic leptin peptide fragment. |
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Related Catalog | |
In Vitro | LEP-(116-130) (300 µM) is unable to inhibit AP-OB binding[1]. |
In Vivo | LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1]. |
Animal Admin | Blood is drawn from the tail vein of each mouse 2 h before the onset of the dark period at the beginning of the study (day 0) and after 2, 4, and 6 days of treatment with 1 mg/day i.p. LEP-(116-130). Blood glucose levels are determined with a Glucometer Elite blood glucose monitor. After 4 and 7 days of treatment with 1 mg/day i.p. LEP-(116-130), sensitivity to cold is examined by placing the mice without food or water in a cold room with an ambient temperature of 4°C. Body temperature is measured with a rectal probe every hour for 4 h. |
References |
Molecular Formula | C64H109N19O24S |
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Molecular Weight | 1560.73000 |
Exact Mass | 1559.76000 |
PSA | 748.38000 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Obese Gene Peptide 116-130 Amide |
LEP (116-130) (mouse) |
Leptin |
SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER: SCSLPQTSGLQKPES |
LEPTIN (116-130) AMIDE |
SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2: SCSLPQTSGLQKPES-NH2 |
LEP(116-130)(mouse) |