NG-497

Modify Date: 2024-01-02 19:13:23

NG-497 Structure
NG-497 structure
Common Name NG-497
CAS Number 2598242-66-9 Molecular Weight 315.36
Density N/A Boiling Point N/A
Molecular Formula C18H21NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NG-497


NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].

 Names

Name NG-497

 NG-497 Biological Activity

Description NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].
Related Catalog
In Vitro NG-497 可选择性地使人和非人灵长类动物 ATGL 失活,但不会使结构和功能相关的脂质水解酶失活,并以剂量依赖性和可逆的方式消除人类脂肪细胞的脂肪分解[1]。 NG-497(40 μM, 80 min)可以减少 HepG2 细胞的脂解依赖性呼吸,并且不会通过脱靶效应损害线粒体功能[1]。
References

[1]. Gernot F Grabner, et al. Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes. J Am Chem Soc. 2022 Apr 13;144(14):6237-6250.  

 Chemical & Physical Properties

Molecular Formula C18H21NO4
Molecular Weight 315.36
Top Suppliers:I want be here


Get all suppliers and price by the below link:

NG-497 suppliers

NG-497 price