ROCK-IN-9

Modify Date: 2024-01-02 18:53:28

ROCK-IN-9 structure	Common Name	ROCK-IN-9
	CAS Number	2643334-76-1	Molecular Weight	381.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₀FN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROCK-IN-9

ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1].

Name	ROCK-IN-9

Description	ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK
References	[1]. Li, Jinping, et al. Rock inhibitor, preparation method therefor and use thereof. WO2021093795.

Molecular Formula	C₂₀H₂₀FN₅O₂
Molecular Weight	381.40

ROCK-IN-9

Use of ROCK-IN-9

Names

ROCK-IN-9 Biological Activity

Chemical & Physical Properties