UR-8880

Modify Date: 2024-01-08 21:10:27

UR-8880 Structure
UR-8880 structure
Common Name UR-8880
CAS Number 265114-23-6 Molecular Weight 381.81
Density 1.49g/cm3 Boiling Point 593.1ºC at 760 mmHg
Molecular Formula C16H13ClFN3O3S Melting Point N/A
MSDS N/A Flash Point 312.5ºC

 Use of UR-8880


Cimicoxib (CX) is an orally active potent and selective COX-2 (cyclo-oxygenase-2) inhibitor. Cimicoxib exhibits promising anti-inflammatory and analgesic activity. The PK parameters of Cimicoxib in dogs given precise (2 mg/kg) and approximate doses (1.95-2.5 mg/kg) are similar[1].

 Names

Name cimicoxib
Synonym More Synonyms

 UR-8880 Biological Activity

Description Cimicoxib (CX) is an orally active potent and selective COX-2 (cyclo-oxygenase-2) inhibitor. Cimicoxib exhibits promising anti-inflammatory and analgesic activity. The PK parameters of Cimicoxib in dogs given precise (2 mg/kg) and approximate doses (1.95-2.5 mg/kg) are similar[1].
Related Catalog
Target

COX-2

References

[1]. Kim TW, Lebkowska-Wieruszewska B, Owen H, Yun HI, Kowalski CJ, Giorgi M. Pharmacokinetic profiles of the novel COX-2 selective inhibitor cimicoxib in dogs. Vet J. 2014 Apr;200(1):77-81.

 Chemical & Physical Properties

Density 1.49g/cm3
Boiling Point 593.1ºC at 760 mmHg
Molecular Formula C16H13ClFN3O3S
Molecular Weight 381.81
Flash Point 312.5ºC
Exact Mass 381.03500
PSA 95.59000
LogP 4.76890
Vapour Pressure 4.91E-14mmHg at 25°C
Index of Refraction 1.649

 Synonyms

4-[4-chloro-5-(3-fluoro-4-methoxyphenyl)imidazol-1-yl]benzenesulfonamide
UR-8880
Cimicoxib
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