1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether

Modify Date: 2024-01-10 14:50:49

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure
1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether structure
Common Name 1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether
CAS Number 26788-23-8 Molecular Weight 302.40800
Density 1.178g/cm3 Boiling Point 472ºC at 760mmHg
Molecular Formula C19H26O3 Melting Point N/A
MSDS N/A Flash Point 239.2ºC

 Use of 1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether


4-Methoxyestradiol is methoxylestradiol that induces oxidative DNA damage in human lung epithelial cells. 4-Methoxyestradiol also elevates ROS and SOD activities in H1355 cells[1].

 Names

Name 4-methoxyestradiol
Synonym More Synonyms

  Biological Activity

Description 4-Methoxyestradiol is methoxylestradiol that induces oxidative DNA damage in human lung epithelial cells. 4-Methoxyestradiol also elevates ROS and SOD activities in H1355 cells[1].
Related Catalog
References

[1]. Yahsin Cheng, et al. 4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells. Toxicol Appl Pharmacol. 2007 May 1;220(3):271-7.  

 Chemical & Physical Properties

Density 1.178g/cm3
Boiling Point 472ºC at 760mmHg
Molecular Formula C19H26O3
Molecular Weight 302.40800
Flash Point 239.2ºC
Exact Mass 302.18800
PSA 49.69000
LogP 3.61780
Vapour Pressure 1.03E-09mmHg at 25°C
Index of Refraction 1.586

 Synthetic Route

~81%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Chen, Shu-hua; Luo, Guan-rong; Wu, Xu-sen; Chen, Min; Zhao, Hua-ming Steroids, 1986 , vol. 47, # 1 p. 63 - 66

~95%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715

~%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715

~%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715

~%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715

~%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715

~%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Literature: Takemura, Hitomi; Uchiyama, Harue; Ohura, Takeshi; Sakakibara, Hiroyuki; Kuruto, Ryoko; Amagai, Takashi; Shimoi, Kayoko Journal of Steroid Biochemistry and Molecular Biology, 2010 , vol. 118, # 1-2 p. 70 - 76

~18%

1,3,5(10)-Estratrien-3,4,17beta-triol 4-methyl ether Structure

1,3,5(10)-Estra...

CAS#:26788-23-8

Detail
Literature: Teranishi; Fujii; Yamazaki; Miyabo Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3309 - 3314

 Synonyms

4-Methoxyestrone
4-Hydroxyestrone-4-methyl ether
4-methoxy-E1
4-methoxy-E2