diethyl 10-bromodecylphosphonate

Modify Date: 2024-01-17 23:06:46

diethyl 10-bromodecylphosphonate Structure
diethyl 10-bromodecylphosphonate structure
Common Name diethyl 10-bromodecylphosphonate
CAS Number 272785-01-0 Molecular Weight 357.26
Density N/A Boiling Point N/A
Molecular Formula C14H30BrO3P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of diethyl 10-bromodecylphosphonate


Diethyl 10-bromodecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diethyl 10-bromodecylphosphonate
Synonym More Synonyms

 diethyl 10-bromodecylphosphonate Biological Activity

Description Diethyl 10-bromodecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H30BrO3P
Molecular Weight 357.26

 Synonyms

MFCD25424104