272785-01-0

272785-01-0 structure
272785-01-0 structure
  • Name: diethyl 10-bromodecylphosphonate
  • Chemical Name: Diethyl 10-bromodecylphosphonate
  • CAS Number: 272785-01-0
  • Molecular Formula: C14H30BrO3P
  • Molecular Weight: 357.26
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:53:36
  • Modify Date: 2024-01-17 23:06:46
  • Diethyl 10-bromodecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Diethyl 10-bromodecylphosphonate
Synonyms MFCD25424104
Description Diethyl 10-bromodecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H30BrO3P
Molecular Weight 357.26