Antiviral agent 35

Antiviral agent 35 structure	Common Name	Antiviral agent 35
	CAS Number	2760972-52-7	Molecular Weight	418.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₈N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antiviral agent 35

Antiviral agent 35 (compound 4d) is an orally active and potent influenza virus inhibitor, acting function in the early stage of virus replication. Antiviral agent 35 inhibits ROS accumulation, autophagy and apoptosis induced by influenza virus, and also inhibits inflammatory response mediated by RIG-1 pathway in mouse model with pulmonary infection. Antiviral agent 35 shows little cytotoxicity with CC50 >800 μM in MDCK cells, and anti-H1N1 (A/Weiss/43) activity with EC50 of 2.28 μM[1].

Name	Antiviral agent 35

Description	Antiviral agent 35 (compound 4d) is an orally active and potent influenza virus inhibitor, acting function in the early stage of virus replication. Antiviral agent 35 inhibits ROS accumulation, autophagy and apoptosis induced by influenza virus, and also inhibits inflammatory response mediated by RIG-1 pathway in mouse model with pulmonary infection. Antiviral agent 35 shows little cytotoxicity with CC50 >800 μM in MDCK cells, and anti-H1N1 (A/Weiss/43) activity with EC50 of 2.28 μM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
Target	EC50: 2.28 μM (HINI A/Weiss/43), 3.34 μM (A/Virginia/ATCC2/2009), 6.61 μM (A/Califomia/2014)[1]
References	[1]. Ge Y, et al. Synthesis and pharmacodynamic evaluation of naphthalene derivatives against influenza A virus in vitro and in vivo. Eur J Med Chem. 2023 Nov 5;259:115660.

Molecular Formula	C₂₃H₁₈N₂O₄S
Molecular Weight	418.47

Antiviral agent 35

Use of Antiviral agent 35

Names

Antiviral agent 35 Biological Activity

Chemical & Physical Properties