Anticancer agent 77

Modify Date: 2024-01-02 15:58:43

Anticancer agent 77 structure	Common Name	Anticancer agent 77
	CAS Number	2787582-75-4	Molecular Weight	508.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₀BrN₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anticancer agent 77

Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research[1].

Name	Anticancer agent 77

Description	Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Anticancer agent 77 (0-1 μM) can inhibit the proliferation of breast cancer cells[1]. Anticancer agent 77 (0-1 μM; 24 h) can induce the apoptosis of breast cancer cells[1]. Cell Proliferation Assay[1] Cell Line: breast cancer cells Concentration: 0, 0.3, and 1 μM Incubation Time: Result: Decreased the number of EdU positive cells in breast cancer in a concentration-dependent manner. Apoptosis Analysis[1] Cell Line: breast cancer cells Concentration: 0, 0.3, and 1 μM Incubation Time: 24 hour Result: Promoted the apoptosis of breast cancer cells compared with the control group.
References	[1]. Jun Xiong, et al. Synthesis of 4-Tetrazolyl-Substituted 3,4-Dihydroquinazoline Derivatives with Anticancer Activity via a One-Pot Sequential Ugi-Azide/Palladium-Catalyzed Azide-Isocyanide Cross-Coupling/Cyclization Reaction. J Org Chem. 2022 Aug 5;87(15):9488-9496.

Molecular Formula	C₂₅H₃₀BrN₇
Molecular Weight	508.46