3-Methoxy-1,5,8-trihydroxyxanthone

Modify Date: 2024-01-02 16:36:45

3-Methoxy-1,5,8-trihydroxyxanthone structure	Common Name	3-Methoxy-1,5,8-trihydroxyxanthone
	CAS Number	2798-25-6	Molecular Weight	274.226
	Density	1.6±0.1 g/cm3	Boiling Point	580.2±50.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₀O₆	Melting Point	265-267ºC
	MSDS	N/A	Flash Point	228.0±23.6 °C

Use of 3-Methoxy-1,5,8-trihydroxyxanthone

Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities[1][2][3]. Bellidifolin also acts as a viral protein R (Vpr) inhibitor[4].

Name	bellidifolin
Synonym	More Synonyms

Description	Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities[1][2][3]. Bellidifolin also acts as a viral protein R (Vpr) inhibitor[4].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology
References	[1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192. [2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63. [3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11. [4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

References

[1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192.

[2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63.

[3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11.

[4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.

Density	1.6±0.1 g/cm3
Boiling Point	580.2±50.0 °C at 760 mmHg
Melting Point	265-267ºC
Molecular Formula	C₁₄H₁₀O₆
Molecular Weight	274.226
Flash Point	228.0±23.6 °C
Exact Mass	274.047729
PSA	100.13000
LogP	0.90
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.714
Storage condition	2-8C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6116500

CHEMICAL NAME :: Xanthen-9-one, 3-methoxy-1,5,8-trihydroxy-

CAS REGISTRY NUMBER :: 2798-25-6

BEILSTEIN REFERENCE NO. :: 0288441

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H10-O6

MOLECULAR WEIGHT :: 274.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

HS Code	2932999099

Swertianolin

CAS#:23445-00-3

3-Methoxy-1,5,8...

CAS#:2798-25-6

Literature: Dhoubhadel, S. P.; Wagley, P. P.; Pradhan, Sabitri Devi Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 929 - 930

Swertianolin

CAS#:23445-00-3

D-glucopyranose

CAS#:2280-44-6

3-Methoxy-1,5,8...

CAS#:2798-25-6

Literature: Ghosal, Shibnath; Biswas, Kanika; Jaiswal, Dinesh K. Phytochemistry (Elsevier), 1980 , vol. 19, p. 123 - 126

Precursor 1
CAS#:23445-00-3 Swertianolin
DownStream 3
CAS#:2980-32-7 Desmethylbellid... CAS#:49599-09-9 1-hydroxy-3,5,8... CAS#:5557-27-7 8-hydroxy-1,3,5...

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,5,8-trihydroxy-3-methoxyxanthone

9H-Xanthen-9-one, 1,5,8-trihydroxy-3-methoxy-

Bellidifolin

3-Methoxy-1,5,8-trihydroxyxanthen-9-one

1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one

bellidifodin

3-Methoxy-1,5,8-trihydroxyxanthone

1,5,8-trihydroxy-3-methoxyxanthen-9-one

1,5,8-Trihydroxy-3-methoxy-xanthen-9-on

1,5,8-trihydroxy-3-methoxy-xanthen-9-one

Bellidifolium

Bellidifoline

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3-Methoxy-1,5,8-trihydroxyxanthone
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
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BioBioPha
China
Product Name: 3-Methoxy-1,5,8-trihydroxyxanthone
Price: ￥1650.0/5mg
Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 3-Methoxy-1,5,8-trihydroxyxanthone
Price: ￥2400.0/5mg
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Bellidifolin
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,5,8-TRIHYDROXY-3-METHOXY-9H-XANTHEN-9-ONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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3-Methoxy-1,5,8-trihydroxyxanthone

Use of 3-Methoxy-1,5,8-trihydroxyxanthone

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