Malvidin-3-O-arabinoside chloride

Modify Date: 2024-01-18 14:03:49

Malvidin-3-O-arabinoside chloride structure	Common Name	Malvidin-3-O-arabinoside chloride
	CAS Number	28500-04-1	Molecular Weight	498.864
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₃O_11.Cl	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Malvidin-3-O-arabinoside chloride

Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy[1].

Name	Malvidin-3-O-arabinoside chloride
Synonym	More Synonyms

Description	Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Metabolic Disease
In Vitro	Malvidin-3-O-arabinoside chloride (M3A chloride, 50-400 μM) pretreatment remarkably upregulates LAMP-1 expression, which indicates elevated lysosomal mass. M3A also successfully restores lysosomal acidity and subsequently strengthenes lysosomal functions. M3A stimulates phosphorylation of AMP-activated protein kinase (AMPK), a master regulator of autophagy[1]. Cell Autophagy Assay[1] Cell Line: Caco-2 cell line. Concentration: 50, 100, 200 and 400 μM. Incubation Time: 24 h (then treated with or without 10 μM chloroquine (CQ) for another 1 h). Result: Notably inhibited excess ROS generation. 200 μM and 400 μM M3A pretreatment significantly enhanced 14% and 16% of GSH level. Enhanced autophagy flux. Significantly up-regulate the LC3-II/LC3-I ratio.
References	[1]. Yuting Li, et al. Malvidin-3-O-arabinoside ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. Food Funct. 2020 Dec 1;11(12):10317-10328.

5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-3-chromeniumyl D-arabinopyranoside chloride

D-Arabinopyranoside, 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-1-benzopyrylium-3-yl, chloride (1:1)

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