Disperse Red 1

Modify Date: 2024-01-06 22:34:51

Disperse Red 1 Structure
Disperse Red 1 structure
Common Name Disperse Red 1
CAS Number 2872-52-8 Molecular Weight 314.33900
Density 1.23 g/cm3 Boiling Point 522.5ºC at 760 mmHg
Molecular Formula C16H18N4O3 Melting Point 160-162 °C(lit.)
MSDS Chinese USA Flash Point 269.8ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Disperse Red 1


Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry[1][2].

 Names

Name Disperse Red 1
Synonym More Synonyms

 Disperse Red 1 Biological Activity

Description Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry[1][2].
Related Catalog
In Vitro Exposure of human lymphocytes and a human hepatoma (HepG2) cell line to Disperse Red 1 in vitro at concentrations of 1.0 μg/mL and 2.0 μg/mL increases the frequency of micronuclei and also causes mutations in the Salmonella assay (13 revertants/μg)[2].
In Vivo To assess the toxic effects of Disperse Red 1 (DR1), on reproduction, sexually mature male mice (Mus musculus, strain CF-1) are orally (gavage) treated with single doses of the compound (20-500 mg/kg). Disperse Red 1 treatment causes testicular toxicity, increases frequency of sperm with abnormal morphology and decreases fertility. An increased amount of DNA damage is also detected in testis cells 16.6 and 24.9 days after treatments with 100 and 500 mg/kg[2].
References

[1]. Laís da Silva Leite, et al. Monitoring Ecotoxicity of Disperse Red 1 Dye During photo-Fenton Degradation. Chemosphere. 2016 Apr;148:511-7.

[2]. Fábio Henrique Fernandes, et al. Disperse Red 1 (Textile Dye) Induces Cytotoxic and Genotoxic Effects in Mouse Germ Cells. Reprod Toxicol. 2015 Jun;53:75-81.

 Chemical & Physical Properties

Density 1.23 g/cm3
Boiling Point 522.5ºC at 760 mmHg
Melting Point 160-162 °C(lit.)
Molecular Formula C16H18N4O3
Molecular Weight 314.33900
Flash Point 269.8ºC
Exact Mass 314.13800
PSA 94.01000
LogP 4.35200
Vapour Pressure 9.57E-12mmHg at 25°C
Index of Refraction 1.602

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL0320000
CHEMICAL NAME :
Ethanol, 2-(ethyl(4-((4-nitrophenyl)azo)phenyl)amino)- (9CI)
CAS REGISTRY NUMBER :
2872-52-8
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C16-H18-N4-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7470 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(1),50,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 gm/kg/30D-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - methemoglobinemia-carboxyhemoglobin Blood - changes in erythrocyte (RBC) count
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(1),50,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2095 No. of Facilities: 479 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 6237 (estimated) No. of Female Employees: 279 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R43
Safety Phrases S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS KL0320000
HS Code 3204110000

 Synthetic Route

~87%

Disperse Red 1 Structure

Disperse Red 1

CAS#:2872-52-8

Literature: Hosseini, S. Hossein; Sarrafi; Hosseini Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2013 , vol. 43, # 7 p. 838 - 846

~%

Disperse Red 1 Structure

Disperse Red 1

CAS#:2872-52-8

Literature: Redy, Orit; Kisin-Finfer, Einat; Sella, Eran; Shabat, Doron Organic and Biomolecular Chemistry, 2012 , vol. 10, # 4 p. 710 - 715

~%

Disperse Red 1 Structure

Disperse Red 1

CAS#:2872-52-8

Literature: Redy, Orit; Kisin-Finfer, Einat; Sella, Eran; Shabat, Doron Organic and Biomolecular Chemistry, 2012 , vol. 10, # 4 p. 710 - 715

~%

Disperse Red 1 Structure

Disperse Red 1

CAS#:2872-52-8

Literature: Kuroki; Konishi Bl.Univ.Osaka Prefect., 1956 , vol. 4, p. 123,128 Full Text Show Details Wahl et al. Bulletin de la Societe Chimique de France, 1952 , p. 366,368 Full Text Show Details Kuroki; Konishi Kogyo Kagaku Zasshi, 1956 , vol. 59, p. 619,622,623 Bl.Univ.Osaka Prefect.Chem.Abstr., 1956 , vol. 4, p. 123,128 Bl.Univ.Osaka Prefect.Chem.Abstr., 1958 , p. 4987

 Customs

HS Code 2927000090
Summary 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles18

More Articles
Assessment of the sensitizing potential of textile disperse dyes and some of their metabolites by the loose-fit coculture-based sensitization assay (LCSA).

Arch. Toxicol. 86(5) , 733-40, (2012)

Certain textile disperse dyes are known to cause allergic reactions of the human skin. Here, we examined 8 disperse dyes and 7 products of azo-cleavage of these dyes in an in vitro assay. We used the ...

Chlorination treatment of aqueous samples reduces, but does not eliminate, the mutagenic effect of the azo dyes Disperse Red 1, Disperse Red 13 and Disperse Orange 1

Mutat. Res. 703(2) , 200-8, (2010)

The treatment of textile effluents by the conventional method based on activated sludge followed by a chlorination step is not usually an effective method to remove azo dyes, and can generate products...

Hepatotoxicity assessment of the azo dyes disperse orange 1 (DO1), disperse red 1 (DR1) and disperse red 13 (DR13) in HEPG2 cells.

J. Toxicol. Environ. Health A 75(16-17) , 991-9, (2012)

During the dyeing process in baths approximately 10 to 15% of the dyes used are lost and reach industrial effluents, thus polluting the environment. Studies showed that some classes of dyes, mainly az...

 Synonyms

Amacel Scarlet GB
Acetate Fast Scarlet B
Dispersol Fast Scarlet B
Acetoquinone Light Scarlet BLZ
2-[N-ethyl-4-[(4-nitrophenyl)diazenyl]anilino]ethanol
4-[Ethyl(2-hydroxyethyl)amino]-4'-nitroazobenzene
EINECS 220-704-3
Dispersive Ruby Zh
Disperse Scarlet Zh
N-Ethyl-N-(2-hydroxyethyl)-4-(4-nitrophenylazo)aniline
Disperse Red Zh
Disperse Scarlet B
Acetamine Scarlet B
MFCD00007312
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