Name | Disperse Red 1 |
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Synonyms |
Amacel Scarlet GB
Acetate Fast Scarlet B Dispersol Fast Scarlet B Acetoquinone Light Scarlet BLZ 2-[N-ethyl-4-[(4-nitrophenyl)diazenyl]anilino]ethanol 4-[Ethyl(2-hydroxyethyl)amino]-4'-nitroazobenzene EINECS 220-704-3 Dispersive Ruby Zh Disperse Scarlet Zh N-Ethyl-N-(2-hydroxyethyl)-4-(4-nitrophenylazo)aniline Disperse Red Zh Disperse Scarlet B Acetamine Scarlet B MFCD00007312 |
Description | Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry[1][2]. |
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Related Catalog | |
In Vitro | Exposure of human lymphocytes and a human hepatoma (HepG2) cell line to Disperse Red 1 in vitro at concentrations of 1.0 μg/mL and 2.0 μg/mL increases the frequency of micronuclei and also causes mutations in the Salmonella assay (13 revertants/μg)[2]. |
In Vivo | To assess the toxic effects of Disperse Red 1 (DR1), on reproduction, sexually mature male mice (Mus musculus, strain CF-1) are orally (gavage) treated with single doses of the compound (20-500 mg/kg). Disperse Red 1 treatment causes testicular toxicity, increases frequency of sperm with abnormal morphology and decreases fertility. An increased amount of DNA damage is also detected in testis cells 16.6 and 24.9 days after treatments with 100 and 500 mg/kg[2]. |
References |
Density | 1.23 g/cm3 |
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Boiling Point | 522.5ºC at 760 mmHg |
Melting Point | 160-162 °C(lit.) |
Molecular Formula | C16H18N4O3 |
Molecular Weight | 314.33900 |
Flash Point | 269.8ºC |
Exact Mass | 314.13800 |
PSA | 94.01000 |
LogP | 4.35200 |
Vapour Pressure | 9.57E-12mmHg at 25°C |
Index of Refraction | 1.602 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H317 |
Precautionary Statements | P280 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xi:Irritant; |
Risk Phrases | R43 |
Safety Phrases | S36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | KL0320000 |
HS Code | 3204110000 |
~87% 2872-52-8 |
Literature: Hosseini, S. Hossein; Sarrafi; Hosseini Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2013 , vol. 43, # 7 p. 838 - 846 |
~% 2872-52-8 |
Literature: Redy, Orit; Kisin-Finfer, Einat; Sella, Eran; Shabat, Doron Organic and Biomolecular Chemistry, 2012 , vol. 10, # 4 p. 710 - 715 |
~% 2872-52-8 |
Literature: Redy, Orit; Kisin-Finfer, Einat; Sella, Eran; Shabat, Doron Organic and Biomolecular Chemistry, 2012 , vol. 10, # 4 p. 710 - 715 |
~% 2872-52-8 |
Literature: Kuroki; Konishi Bl.Univ.Osaka Prefect., 1956 , vol. 4, p. 123,128 Full Text Show Details Wahl et al. Bulletin de la Societe Chimique de France, 1952 , p. 366,368 Full Text Show Details Kuroki; Konishi Kogyo Kagaku Zasshi, 1956 , vol. 59, p. 619,622,623 Bl.Univ.Osaka Prefect.Chem.Abstr., 1956 , vol. 4, p. 123,128 Bl.Univ.Osaka Prefect.Chem.Abstr., 1958 , p. 4987 |
Precursor 4 | |
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DownStream 1 | |
HS Code | 2927000090 |
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Summary | 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |