BI‑3231

Modify Date: 2024-01-30 20:15:39

BI‑3231 structure	Common Name	BI‑3231
	CAS Number	2894848-07-6	Molecular Weight	380.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₄F₂N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BI‑3231

BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases[1].

Name	BI‑3231

Description	BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13)[1]
In Vitro	BI 3231 在肝微粒体中表现出高代谢稳定性，在肝细胞中表现出中等代谢稳定性[1]。
In Vivo	BI 3231 从血浆中迅速清除，但在 48 h 内仍保持相当大的肝脏暴露[1]。
References	[1]. Thamm S, et, al. Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science. J Med Chem. 2023 Feb 2.

Molecular Formula	C₁₆H₁₄F₂N₄O₃S
Molecular Weight	380.37

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BI‑3231
Price: Negotiable
Purity: 98.2%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: BI?3231
Price: ￥2432.0/100mg
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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